Methodological Factors RCTs
Examining the Impact of Methodological Factors on the Magnitude of Treatment Effects in Dental and Nursing Randomized Controlled Trials Using a Meta-Epidemiological Approach
Start/End Dates: 2014 – 2015
Investigators: Cummings GG (PI), Flores Mir C, Armijo-Olivo S, Egger M, da Costa B, Juni P, Saltaji H, Straus S.
Funder: UA/AIHS Bridging Grant
Grant Amount: $40,000
This study seeks to measure the association between methodological characteristics and treatment effect estimates in dentistry and nursing RCTs. Determining the influence of RCT and specialty characteristics on treatment effect estimates will allow us to develop guidelines for the design, conduct, reporting, and implementation of RCTs in dentistry and nursing. This study will also provide specific benchmarks for evaluating risk of bias for these RCTs.
It is a continuation of Dr. Armijo-Olivo's CIHR Banting Postdoctoral Fellowship Program project ($175,000), Informed Decision Making in Health Care: the Impact of Research Methods on Treatment Recommendations.